Membrane messengers: Extracellular vesicles
نویسندگان
چکیده
منابع مشابه
Extracellular Vesicles Act as Messengers of Macrophages Sensing Atherogenic Stimuli.
The release of vesicles by cells into the extracellular space is found in many aspects of biology, and such extracellular vesicles (EVs) are gaining increasing attention in diverse areas of biomedical research. EVs represent a heterogeneous population differing in size, number, and composition that are dependent on the type and activation state of the parental cells that release them. Based on ...
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Blood-borne monocyte derived cells play a pivotal, initially unrecognized, role in most central nervous system disorders, including diseases initially classified as purely neurodegenerative (i.e., Alzheimer's disease, Parkinson's disease, and ALS). Their trafficking to the brain and spinal cord has been extensively studied in classical neuroinflammatory disorders such as multiple sclerosis. Cen...
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Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane vesicles, with distinct biogenesis routes, biophysical properties and different functions both in physiological conditions and in disease. The release of EVs is a widespread biological process, which is conserved across species. In recent years, numerous studies have demonstrated that several bioactive molecules ar...
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The capacity to regulate their internal ionic composition is a fundamental property of free-living terrestrial organisms (Stewari and Broadus, 1987). This is accomplished by adjusting the movement of ions or water (or both) between cells and various extracellular compartments, including those communicating with the external environment. Of the complement of inorganic ions in such organisms, Ca2...
متن کاملEXTRACELLULAR VESICLES AND THEIR THERAPEUTIC APPLICATIONS: A REVIEW
Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells. These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...
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ژورنال
عنوان ژورنال: Science
سال: 2016
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.opms.p1600106